Arsenal kick off their 2015/16 season with a home clash against West Ham on Sunday, and they have a number of injury concerns to contend with.
Arsene Wenger has lost Jack Wilshere for up-to-six-weeks following a training ground clash that left him with a hairline fracture in his leg.
Meanwhile, both Danny Welbeck and Tomas Rosicky are still out with knee injuries, and Alexis Sanchez is still some way off returning to action after his prolonged break following the Copa America.
Every NEW Premier League kit RATED: 40 strips ASSESSED
2015-16 Premier League title & top 4 battles predicted: Chelsea, Arsenal, Liverpool & Man U in the mix
Man United squad numbers
As a result, Wenger will have to do some tinkering with his side as they welcome West Ham to the Emirates who will be looking to give Slaven Bilic the perfect start to life as a manager in the Premier League.
The Croatian ace returns to the club this season after previously playing for them, and although they failed in the Europa League qualifiers, they could be that little bit sharper than their rivals on Sunday.
Nevertheless, they may find scoring goals a problem given that Enner Valencia joined Andy Carroll in the treatment room after suffering a knee injury that will keep him out for two months.
However, Bilic has brought in plenty of exciting talent this summer, and he will hope to see that pay off and try to play the Gunners at their own game.
Arsenal have won nine of their last 14 opening day games, while no team has lost more opening day fixtures than West Ham (nine).
As a result, Bilic and the visitors may well face a tough time changing the history books on Sunday afternoon.