The midfielder will take charge for the remaining four matches.
Manchester United have sacked manager David Moyes and have appointed Ryan Giggs as interim until the end of the season.
The 50-year-old was in charge for just 10 months at Old Trafford despite being given a bumper six-year contract after succeeding Sir Alex Ferguson in the summer of 2013.
Many predicted that it would be tough for Moyes to try and emulate the success his fellow countryman had with the Red Devils during 26-and-a-half years in charge.
Giggs will now take over for the remaining four Premier League matches left in this season as the English champions search for a successor.
The midfielder has been on Moyes’ coaching staff this year and will be aided by a former United star in the shape of Nicky Butt.
Giggs is one of the favourites to take the job on a permanent basis, along with Atletico Madrid head coach Diego Simeone, Jurgen Klopp of Borussia Dortmund and Netherlands national team boss Louis van Gaal.
Moyes leaves the club after guiding them to their 11th league defeat of the season against former side Everton on Sunday.
That loss to the Toffees leaves the reigning champions unlikely to qualify for any European competition for next term and finishing with the lowest points tally of any defending title holder.
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