Two teams with perfect records in what should be one of the the games of the round.
One team will have their unbeaten record broken this NFL season when Tom Brady and the New England Patriots take on Drew Brees and the New Orleans Saints.
Tight end Rob Gronkowski is hoping to take the field for the first time this season as the Patriots try to rebound against the Saints after losing 13-6 to the Cincinnati Bengals last weekend.
New England has won its first four games despite a subpar showing so far on offence. It finally caught up to them in last weekend’s loss as they scored their fewest points in a game since 2006.
Brady was limited to 197 yards on 18-of-38 throwing.
The 24-year-old Gronkowski had a terrific season in 2011, logging 1,327 receiving yards and 18 touchdowns, and had 55 catches for 790 yards last year before breaking his forearm.
He returned for the playoffs, but again broke the forearm. Gronkowski had three surgeries this past offseason.
Peyton Manning’s red-hot Denver Broncos face the winless Jacksonville Jaguars in Colorado.
While the Broncos have been brilliant through a 5-0 start, the hapless Jaguars are being compared to all-time lowly squads, including their own 4-12 team of 1995.
Denver has also won 16 consecutive regular-season games, while the Jaguars have dropped 10 straight.
Dallas quarterback Tony Romo will be looking to bounce back as the Cowboys take on the Washington Redskins.
Romo and the Cowboys are coming off an emotional loss at home and face another stiff challenge Sunday against the NFC East rival Redskins.
The Cowboys came so close to upending Manning and the Broncos in last weekend’s 51-48 loss, but a late interception by Romo allowed the visitors to march into scoring position and kick a game-winning field goal.
The interception by Romo, just the second of the season, was his only flaw of the game and eventually dropped the Cowboys to 2-3.
The Redskins are 0-1 in the NFC East and winless against the conference this season, while Dallas is 1-0 in the division and 2-0 in the NFC.
In other games this weekend it is, Green Bay at Baltimore, Philadelphia at Tampa Bay, Pittsburgh at NY Jets, Carolina at Minnesota, Oakland at Kansas City, St. Louis at Houston, Cincinnati at Buffalo, Detroit at Cleveland, Tennessee at Seattle and Arizona at San Francisco. The Monday night contest has Indianapolis visiting San Diego.