Tom Cleverley, Phil Jones, Wayne Rooney and Chris Smalling – ENGLAND v Chile (Nov 15), Germany (Nov 19)
The Three Lions face two tough sides in Chile and Germany at Wembley and two of United’s aces Michael Carrick and Danny Welbeck have already pulled out of the matches.
However, it will be a chance for players on the outskirts of the squad – such as Cleverley and Smalling – to justify their inclusion.
Patrice Evra – FRANCE v Ukraine (Nov 15 & 19)
After finishing second behind Spain in their qualification group, the French have to undergo a tricky play-off round with Ukraine.
Evra has been reinstated in the squad after making comments about commentators and will need to be on top form to guide the nation through.