Spurs start with a trip across London to Selhurst Park.
Slow starters Tottenham will begin the season with a trip to newly-promoted Crystal Palace before hosting Swansea City at White Hart Lane.
The first north London derby with Arsenal with take place before the start of September at the Emirates Stadium in just the third match of the campaign, before a return leg at White Hart Lane on 15 March.
Other Premier League new boys Cardiff City and Hull City will both play Tottenham before November.
Spurs boss Andre Villas-Boas will go head-to-head with his former mentor Jose Mourinho – now Chelsea boss – for the first time on 28 September at the Lane and Spurs will travel to Stamford Bridge on 8 March – directly before their meeting with Arsenal.
The north Londoners also face Man City and Man United back-to-back at the end of November but face a pleasant-looking run-in with no games against the traditionally ‘big’ clubs in April or May.