Wisconsin are a No.1 seed for the first time in school history, and they will be hoping to live up to it starting against Coastal Carolina on Friday.
Where: CenturyLink Center, Omaha.
When: Friday March 20, 21:20 (ET)
The Badgers are 31-3 for the season and will be looking for their second straight trip to the Final Four this year but will begin with a tricky encounter with the Chanticleers who are 24-9.
It is a second consecutive appearance at the NCAA Tournament for the underdogs, but they are 0-3 all-time and so will need something special to put one up in the win column.
One area of the game that they do well in is rebounding, as they rank fifth in the NCAA with 39.8 per game, and they will need a strong showing on the boards to give them an edge on both ends of the floor.
However, they will need an all-round performance to oust the favourites in this one, with Wisconsin making their 17th consecutive appearance in the competition and 21st overall.
With a 29-19 overall record, they know what it takes to win in the early rounds at least and they are 15-5 in opening round games through their history.
While they have various strengths, the one thing that the Badgers do really well is look after the ball, as they average just 7.4 turnovers per game which is the lowest rate in the nation.
They will have do it without guard Traevon Jackson though, who has missed the last 17 games with an ankle injury and is questionable to play.
In his absence, look for Big Ten Player of the Year Frank Kaminsky to lead the Badgers as he averages 18.2 points, 8.0 rebounds and 1.6 blocked shots per game.
Warren Gillis will look to lead the upset for Coastal Carolina as he averages a team-high 13.1 points per game while also grabbing 3.1 rebounds, dishing out 3.2 assists and making 1.4 steals each contest.