Watch the clash from Murrayfield.
Where: Murrayfield, Edinburgh.
When: Sunday 15 February, 15.00 GMT.
Watch live: Click here to watch on BBC Sport!
Wales have been left somewhat winded in the Six Nations after a surprising defeat at the Millennuim Stadium to England in their opener and there could be no better time for Scotland to host them at Murrayfield.
Defeat for the Welsh would essentially mean their title hopes are over just two games in and there has been further criticism aimed at the side over failing to sub George North after suspected concussion against the English.
The Scots will also have been given hope after their performance against France last weekend, with a spirited showing in Paris suggesting it won’t be a 51-3 rout like last year.
Stuart Hogg will be the danger man for the home side, but with the likes of Leigh Halfpenny and Jamie Roberts at their disposal, Warren Gatland’s men will still be the favourites for this clash.