RB: Hector Bellerin
Put your wellies on, because Arsenal are knee-deep in options here. Calum Chambers, Mathieu Debuchy and Bellerin are all vying for a starting spot. Remember, Carl Jenkinson is on loan at West Ham United.
The young Spaniard finished last season in possession and should be given first crack at making the right-back position his own, starting against Lyon.
CB: Laurent Koscielny
Arsenal’s best centre-back by a mile, the Gunners are simply much better when Koscielny plays, and he might need to be on top form to restrain 29-goal Lyon striker Alexandre Lacazette.
Finding a partner for the dependable Frenchman should be one of Wenger’s priority with this massive £200m transfer kitty that he has suddenly stumbled upon, as the Daily Mail reports.
CB: Per Mertesacker
Should he approach this game with as much tactical thought as he does every other, Wenger might plump for Gabriel Paulista instead of Mertesacker because of the pace of the Lyon attack.
But the Gunners boss might want his first-choice defensive pairing to reacquaint themselves after the summer break.
LB: Nacho Monreal
The Spaniard has been linked with a return to La Liga with Athletic Bilbao [talkSPORT], but remains an Arsenal player as it stands and ahead of Kieran Gibbs in the running to be first-choice left-back.