Out of form Panthers look to break four-game losing streak as they head to the Hunter.
Penrith coach Ivan Cleary is persisting with halves pairing Tom Humble and Blake Austin ahead of their clash against the Newcastle Knights at Hunter Stadium in round six.
Humble and Austin, who only have 39 NRL matches between them, have been used as the five-eighth and halfback respectively early this season.
However, much like the rest of the side, the combination has yet to fire for the Panthers who were crushed by 30 points by Jonathan Thurston and the North Queensland Cowboys last round.
A completion rate of just 64 per cent when combined with 27 missed tackles gave the Cowboys all the chances they needed to rack up the points.
The only injury news for the Knights this round is the return of veteran hooker Danny Buderus, who was a late withdrawal last round due to a back injury.
Knights: Darius Boyd, James McManus, Alex McKinnon, Timana Tahu, Akuila Uate, Jarrod Mullen, Tyrone Roberts, Kade Snowden, Kurt Gidley (c), Willie Mason, Robbie Rochow, Chris Houston, Jeremy Smith. Interchange: Danny Buderus, Neville Costigan, Adam Cuthbertson, David Fa’alogo
Panthers: Dean Whare, Josh Mansour, Wes Naiqama, Brad Tighe, David Simmons, Tom Humble, Blake Austin, Sam McKendry, Kevin Kingston (c), Nigel Plum, Sika Manu, Lewis Brown, Cameron Ciraldo. Interchange: Adam Docker, Tim Grant, James Segeyaro, Clint Newton