Glaswegian will depart after remaining two top-flight fixtures of this campaign.
Everton have confirmed that manager David Moyes will be leaving the club at the end of this season, with the Scot expected to take over at Premier League champions Manchester United with immediate effect.
The former Preston North End coach, who arrived at Goodison Park in 2002, will now take charge of the Toffees’ final two top-flight fixtures of this season, at home to West Ham United on Sunday and then away at Chelsea seven days later.
Moyes, 50, has overseen 516 Everton games in an 11-year period, winning 217 and losing 160 of those contests, with a win percentage of 42.
And, during his time on Merseyside the Glaswegian has taken the club from a struggling Premier League outfit to a regular contender for the Uefa Champions League, with Everton’s highest finish under his stewardship coming in 2005 when they were fourth in the table.
Meanwhile, the closest that Moyes got to winning a trophy with Everton came in 2009 when they lost to Chelsea 2-1 in the FA Cup final.
A statement on the official Everton website on Thursday afternoon said: “Everton can confirm that David Moyes will leave the Club at the end of the season.
The Manager met Chairman Bill Kenwright early yesterday evening (Wednesday 8th May) and confirmed his desire to join Manchester United.
The Chairman, on behalf of the Club, would like to place on record his thanks to David for the massive contribution he has made to Everton since his arrival in March 2002. He has been an outstanding Manager.
During his tenure at Goodison Park, David has taken charge of the team on over 500 occasions including four European campaigns.
His final two games as Everton Manager will be the remaining Premier League matches against West Ham United and Chelsea.
Everton officials will start the search for a replacement manager immediately.”