Knee injury rules flanker out of the entire tournament.
England will be without flanker Tom Johnson for the entire Six Nations due to a knee injury which will keep the player out of action for up to three months.
Buy Six Nations tickets to England v Scotland at Twickenham on Feb 2.
Johnson, 30, won the last of his five England caps against Australia in November.
Meanwhile, loosehead prop Alex Corbisiero will miss England’s opening two fixtures, against Scotland and Ireland, while his longstanding knee injury is ‘cleaned out’.
England will also be without Freddie Burns for at least the Scotland game at Twickenham on February 2, with the Gloucester fly-half set to be sidelined for up to three weeks with knee ligament damage.
Lancaster added that it was “too early to tell” whether centre Manu Tuilagi, one of England’s try-scorers in their dramatic 38-21 win over world champions New Zealand last time out in December, will have recovered from an ankle injury in time for the Calcutta Cup clash against the Scots.
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