The two bottom sides on the NRL table meet when the Gold Coast Titans travel south to tackle the Cronulla Sharks.
Where: Remondis Stadium, Sydney
When: 6.30am Saturday 28th March (5.30pm local)
Watch live: Premier Sports
Both teams have yet to win a game in the current campaign and are desperate for some relief.
The Titans were much better in round three and were unlucky to lose to Newcastle. A couple of crucial calls went against them which made all the difference.
They will be hoping for better luck this weekend. Former National Youth Competition Player of the Year Kane Elgey will make his NRL debut in place of Daniel Mortimer.
Mortimer is out for the next two weeks with a wrist injury, while Agnatius Paasi has been named on an extended bench.
Cronulla have made a large number of changes with Ben Barba banned and Wade Graham has shifted to five-eighth. Anthony Tupou will start in the back row, Sam Tagataese is out and Chris Heighington will start at prop.
Matt Prior has come on to the bench along with Jack Bird, who will make his NRL debut.