Both teams looking to kick-start their seasons after sluggish starts.
Where: FedEx Field
When: 18.00 (BST)
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The Detroit Lions will have a tough choice to make as to who is their starting running back for their week three clash with the Washington Redskins with Reggis Bush still in doubt.
Bush injured his knee in his side’s 25-21 loss to Arizona last week and has been bothered by the complaint all week and is only listed as questionable for game time.
Rookie Theo Riddick is the most likely to get the call up after being called into the game when Bush was injury, and after starring with Notre Dame in his college career, Bush beleives his understudy has what it takes to step up if needed.
“His maturity level has grown since Day 1, since he stepped on the field here,” Bush said.
“Seeing where he’s come from up until now, he’s a really good player and I think he’s going to be around for a long time.
“I think he has a lot to offer this team and our offense.”
Detroit has had mixed fortunes in its two games this season with a 10-point win over Minnesota contrasted with a loss to the Cardinals with their 1-1 record seeing them sit in second place on the NFC North.
Others injury worries for the Lions include defensive tackle Nick Fairley who was on limited practice this week and is listed as questionable.
Guard Rob Sims (knee), linebacker Ashlee Palmer (ankle) and defensive end Jason Jones (knee) are all listed as probably despite having mixed training efforts this week.
Washington will be desperate to win against the Lions and get their flagging season fortunes off the ground after losing both games to date.
Many pundits are wondering if quarterback Robert Griffin III came back too early from surgery to his ACL, with the second year paying lacking the spark that was a feature of his first year in the league.
So far this season Griffin III has thrown 56-89 for five touchdowns and, worryingly, three interceptions.